rat HSD17B6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Hsd17b6.
shADV-292545
Ad-r-HSD17B6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Hsd17b6 (hydroxysteroid (17-beta) dehydrogenase 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Hsd17b9
Description (Vector)
NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro). Can convert androsterone to epi-androsterone. Androsterone is first oxidized to 5-alpha-androstane-3,17-dione and then reduced to epi-andosterone. Can act on both C-19 and C-21 3-alpha-hydroxysteroids.
Gene ID
286964
Gene Name (Vector)
hydroxysteroid (17-beta) dehydrogenase 6
Gene Symbol
Hsd17b6
ORF Size (aa)
984
ORF Size (bp)
984 bp
RefSeq ID
NM_173305
RefSeq Synonyms
NM_173305, BC091114, BC088104,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.