rat GRINL1A shRNA silencing Adenovirus

Name
Ad-r-GRINL1A-shRNA

Cat No
shADV-291981

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Polr2m.

shADV-291981

Ad-r-GRINL1A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Polr2m (RNA polymerase II subunit M). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

Glurr; Grinl1a

Description (Vector)

Isoform 1 appears to be a stable component of the Pol II(G) complex form of RNA polymerase II (Pol II). Pol II synthesizes mRNA precursors and many functional non-coding RNAs and is the central component of the basal RNA polymerase II transcription machinery. Isoform 1 may play a role in the Mediator complex-dependent regulation of transcription activation. Isoform 1 acts in vitro as a negative regulator of transcriptional activation; this repression is relieved by the Mediator complex, which restores Pol II(G) activator-dependent transcription to a level equivalent to that of Pol II.

Gene ID

192147

Gene Name (Vector)

RNA polymerase II subunit M

Gene Symbol

Polr2m

ORF Size (aa)

1095

ORF Size (bp)

1095 bp

RefSeq ID

NM_183402

RefSeq Synonyms

NM_183402, BC079379,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.