rat GGT1 shRNA silencing Adenovirus

Name 
Ad-r-GGT1-shRNA
Cat No 
shADV-291948
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Ggt1.

shADV-291948
Ad-r-GGT1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Ggt1 (gamma-glutamyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
81
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GGLUT; Ggt; Ggtp
Description (Vector)
Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate. Isoform 3 seems to be inactive.
Gene ID
116568
Gene Name (Vector)
gamma-glutamyltransferase 1
Gene Symbol
Ggt1
ORF Size (aa)
1707
ORF Size (bp)
1707 bp
RefSeq ID
NM_053840
RefSeq Synonyms
NM_053840, BC078768,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.