rat NDE1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Nde1.
shADV-291603
Ad-r-NDE1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Nde1 (nudE neurodevelopment protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Nude
Description (Vector)
Required for centrosome duplication and formation and function of the mitotic spindle. Essential for the development of the cerebral cortex. May regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a post-mitotic neuron. A premature shift towards a neuronal fate within the progenitor population may result in an overall reduction in the final number of neurons and an increase in the number of neurons in the deeper layers of the cortex.
Gene ID
83836
Gene Name (Vector)
nudE neurodevelopment protein 1
Gene Symbol
Nde1
ORF Size (aa)
1038
ORF Size (bp)
1038 bp
RefSeq ID
NM_053347
RefSeq Synonyms
NM_053347, BC081759,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.