rat ANGPTL4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Angptl4.
shADV-291017
Ad-r-ANGPTL4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Angptl4 (angiopoietin-like 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation (By similarity).
Gene ID
362850
Gene Name (Vector)
angiopoietin-like 4
Gene Symbol
Angptl4
ORF Size (aa)
1218
ORF Size (bp)
1218 bp
RefSeq ID
NM_199115
RefSeq Synonyms
NM_199115, BC078944,
Species
rat
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.