rat LIPA shRNA silencing Adenovirus

Name 
Ad-r-LIPA-shRNA
Cat No 
shADV-290708
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Lipa.

shADV-290708
Ad-r-LIPA-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Lipa (lipase A, lysosomal acid type). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Chole; Chole2; LAL; Lip1
Description (Vector)
Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.
Gene ID
25055
Gene Name (Vector)
lipase A, lysosomal acid type
Gene Symbol
Lipa
ORF Size (aa)
1194
ORF Size (bp)
1194 bp
RefSeq ID
NM_012732
RefSeq Synonyms
NM_012732, BC072532,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.