rat PPP1R15A shRNA silencing Adenovirus

Name 
Ad-r-PPP1R15A-shRNA
Cat No 
shADV-290706
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Ppp1r15a.

shADV-290706
Ad-r-PPP1R15A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Ppp1r15a (protein phosphatase 1, regulatory subunit 15A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
74
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Gadd34; Myd116; Peg-3; RGD1624209
Description (Vector)
Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.
Gene ID
171071
Gene Name (Vector)
protein phosphatase 1, regulatory subunit 15A
Gene Symbol
Ppp1r15a
ORF Size (aa)
1737
ORF Size (bp)
1737 bp
RefSeq ID
NM_133546
RefSeq Synonyms
NM_133546, BC072513,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.