rat PRKAB1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Prkab1.
shADV-290564
Ad-r-PRKAB1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Prkab1 (protein kinase AMP-activated non-catalytic subunit beta 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
Gene ID
83803
Gene Name (Vector)
protein kinase AMP-activated non-catalytic subunit beta 1
Gene Symbol
Prkab1
ORF Size (aa)
813
RefSeq ID
NM_031976
RefSeq Synonyms
NM_031976, BC062008,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.