rat HDAC3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Hdac3.
shADV-290560
Ad-r-HDAC3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Hdac3 (histone deacetylase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation (By similarity).
Gene ID
84578
Gene Name (Vector)
histone deacetylase 3
Gene Symbol
Hdac3
ORF Size (aa)
1287
ORF Size (bp)
1287 bp
RefSeq ID
NM_053448
RefSeq Synonyms
NM_053448, BC061988,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.