mouse HSD3B1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Hsd3b1.
shADV-280809
Ad-m-HSD3B1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Hsd3b1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
3-beta-HSD I; D3Ertd383e
Description (Vector)
3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. Efficiently catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17-alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta,17 beta-diol, dehydroepiandrosterone to androstenedione and 5-alpha-androstan-3 beta,17 beta-diol to 5-alpha-dihydrotestosterone.
Gene ID
15492
Gene Name (Vector)
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Gene Symbol
Hsd3b1
ORF Size (aa)
1122
ORF Size (bp)
1122 bp
RefSeq ID
NM_008293
RefSeq Synonyms
NM_008293, NM_001304800, BC052659,
Species
mouse
UniGene ID
Mm.140811
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.