mouse ADM shRNA silencing Adenovirus

Name
Ad-m-ADM-shRNA

Cat No
shADV-280532

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Adm.

shADV-280532

Ad-m-ADM-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Adm (adrenomedullin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

Description (Vector)

AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.

Gene ID

11535

Gene Name (Vector)

adrenomedullin

Gene Symbol

Adm

ORF Size (aa)

555

ORF Size (bp)

555 bp

RefSeq ID

NM_009627

RefSeq Synonyms

NM_009627, BC052665,

Species

mouse

UniGene ID

Mm.1408

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.