mouse CRBN shRNA silencing Adenovirus

Name 
Ad-m-CRBN-shRNA
Cat No 
shADV-280509
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Crbn.

shADV-280509
Ad-m-CRBN-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Crbn (cereblon). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2610203G15Rik; 2900045O07Rik; AF229032; AW108261; piL
Description (Vector)
Component of some DCX (DDB1-CUL4-X-box) E3 protein ligase complex, a complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins and is required for limb outgrowth and expression of the fibroblast growth factor FGF8. In the complex, may act as a substrate receptor. Regulates the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning via its interaction with KCNT1.
Gene ID
58799
Gene Name (Vector)
cereblon
Gene Symbol
Crbn
ORF Size (aa)
1296
ORF Size (bp)
1296 bp
RefSeq ID
NM_021449
RefSeq Synonyms
NM_175357, NM_021449, BC086488,
Species
mouse
UniGene ID
Mm.290085

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.