mouse ARG2 shRNA silencing Adenovirus

Name
Ad-m-ARG2-shRNA

Cat No
shADV-278070

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Arg2.

shADV-278070

Ad-m-ARG2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Arg2 (arginase type II). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

AII; AU022422

Description (Vector)

ARG2 may play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.

Gene ID

11847

Gene Name (Vector)

arginase type II

Gene Symbol

Arg2

ORF Size (aa)

1065

ORF Size (bp)

1065 bp

RefSeq ID

NM_009705

RefSeq Synonyms

NM_009705, BC023349,

Species

mouse

UniGene ID

Mm.3506

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.