mouse TRPC4AP shRNA silencing Adenovirus

Name 
Ad-m-TRPC4AP-shRNA
Cat No 
shADV-277324
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Trpc4ap.

shADV-277324
Ad-m-TRPC4AP-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Trpc4ap (transient receptor potential cation channel, subfamily C, member 4 associated protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
4833429F06Rik; D2Ertd113e; mFLJ00177; Trrp4ap; truss
Description (Vector)
Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.
Gene ID
56407
Gene Name (Vector)
transient receptor potential cation channel, subfamily C, member 4 associated protein
Gene Symbol
Trpc4ap
ORF Size (aa)
2394
ORF Size (bp)
2394 bp
RefSeq ID
NM_019828
RefSeq Synonyms
NM_019828, NM_001163452, BC057330, BC033274,
Species
mouse
UniGene ID
Mm.268304

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.