mouse WHSC2 shRNA silencing Adenovirus

Name 
Ad-m-WHSC2-shRNA
Cat No 
shADV-276289
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Nelfa.

shADV-276289
Ad-m-WHSC2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Nelfa (negative elongation factor complex member A, Whsc2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Whsc2; Whsc2h
Description (Vector)
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. Probably required to interact with the RNA polymerase II complex.
Gene ID
24116
Gene Name (Vector)
negative elongation factor complex member A, Whsc2
Gene Symbol
Nelfa
ORF Size (aa)
1593
ORF Size (bp)
1593 bp
RefSeq ID
NM_011914
RefSeq Synonyms
NM_011914, BC038003,
Species
mouse
UniGene ID
Mm.332320

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.