mouse DNAJA3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Dnaja3.
shADV-275968
Ad-m-DNAJA3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Dnaja3 (DnaJ heat shock protein family (Hsp40) member A3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1200003J13Rik; 1810053A11Rik; C81173; Tid-1; Tid1l
Description (Vector)
Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma-mediated transcriptional activity. Isoform 2 may play a role in neuromuscular junction development as an effector of the MUSK signaling pathway.
Gene ID
83945
Gene Name (Vector)
DnaJ heat shock protein family (Hsp40) member A3
Gene Symbol
Dnaja3
ORF Size (aa)
1362
ORF Size (bp)
1362 bp
RefSeq ID
NM_023646
RefSeq Synonyms
NM_023646, NM_001135112, BC027240,
Species
mouse
UniGene ID
Mm.248337
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.