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mouse TTC3 shRNA silencing Adenovirus

Name 
Ad-m-TTC3-shRNA
Cat No 
shADV-275235
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Ttc3.

shADV-275235
Ad-m-TTC3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ttc3 (tetratricopeptide repeat domain 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
51
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2610202A04Rik; AA409221; D16Ium21; D16Ium21e; mKIAA4119; TPRD
Description (Vector)
E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation; its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.
Gene ID
22129
Gene Name (Vector)
tetratricopeptide repeat domain 3
Gene Symbol
Ttc3
ORF Size (aa)
5940
ORF Size (bp)
5940 bp
RefSeq ID
NM_009441
RefSeq Synonyms
NM_009441, BC167169,
Species
mouse
UniGene ID
Mm.213408

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.