mouse TNFSF11 shRNA silencing Adenovirus

Name 
Ad-m-TNFSF11-shRNA
Cat No 
shADV-274722
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Tnfsf11.

shADV-274722
Ad-m-TNFSF11-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Tnfsf11 (tumor necrosis factor (ligand) superfamily, member 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Ly109l; ODF; OPGL; RANKL; Trance
Description (Vector)
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.
Gene ID
21943
Gene Name (Vector)
tumor necrosis factor (ligand) superfamily, member 11
Gene Symbol
Tnfsf11
ORF Size (aa)
951
ORF Size (bp)
951 bp
RefSeq ID
NM_011613
RefSeq Synonyms
NM_011613, BC131970, BC125603,
Species
mouse
UniGene ID
Mm.249221

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.