mouse TLE3 shRNA silencing Adenovirus

Name 
Ad-m-TLE3-shRNA
Cat No 
shADV-274262
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Tle3.

shADV-274262
Ad-m-TLE3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Tle3 (transducin-like enhancer of split 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2610103N05Rik; ESG; Grg3a; Grg3b; mKIAA1547
Description (Vector)
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity).
Gene ID
21887
Gene Name (Vector)
transducin-like enhancer of split 3
Gene Symbol
Tle3
ORF Size (aa)
2349
ORF Size (bp)
2349 bp
RefSeq ID
NM_009389
RefSeq Synonyms
NM_009389, NM_001083928, NM_001083927, BC056465,
Species
mouse
UniGene ID
Mm.469199

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.