mouse TICAM1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Ticam1.
shADV-274195
Ad-m-TICAM1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ticam1 (toll-like receptor adaptor molecule 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AW046014; AW547018; TICAM-1; TRIF
Description (Vector)
Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.
Gene ID
106759
Gene Name (Vector)
toll-like receptor adaptor molecule 1
Gene Symbol
Ticam1
ORF Size (aa)
2199
ORF Size (bp)
2199 bp
RefSeq ID
NM_174989
RefSeq Synonyms
NM_174989, BC094338,
Species
mouse
UniGene ID
Mm.203952
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.