mouse TFB2M shRNA silencing Adenovirus

Name 
Ad-m-TFB2M-shRNA
Cat No 
shADV-274081
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Tfb2m.

shADV-274081
Ad-m-TFB2M-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Tfb2m (transcription factor B2, mitochondrial). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Hkp1
Description (Vector)
S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
Gene ID
15278
Gene Name (Vector)
transcription factor B2, mitochondrial
Gene Symbol
Tfb2m
ORF Size (aa)
1191
ORF Size (bp)
1191 bp
RefSeq ID
NM_008249
RefSeq Synonyms
NM_008249, NM_001331055, NM_001331054, BC138837, BC138836,
Species
mouse
UniGene ID
Mm.293529

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.