mouse SUV39H2 shRNA silencing Adenovirus

Name 
Ad-m-SUV39H2-shRNA
Cat No 
shADV-273486
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Suv39h2.

shADV-273486
Ad-m-SUV39H2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Suv39h2 (suppressor of variegation 3-9 homolog 2 (Drosophila)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
4930507K23Rik; AA536750; D030054H19Rik; D2Ertd544e; KMT1B
Description (Vector)
Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May participate in regulation of higher order chromatin organization during spermatogenesis.
Gene ID
64707
Gene Name (Vector)
suppressor of variegation 3-9 homolog 2 (Drosophila)
Gene Symbol
Suv39h2
ORF Size (aa)
774
ORF Size (bp)
774 bp
RefSeq ID
NM_022724
RefSeq Synonyms
NM_022724, BC032960,
Species
mouse
UniGene ID
Mm.441181

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.