mouse SPRY4 shRNA silencing Adenovirus

Name 
Ad-m-SPRY4-shRNA
Cat No 
shADV-273096
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Spry4.

shADV-273096
Ad-m-SPRY4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Spry4 (sprouty homolog 4 (Drosophila)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
A030006O18Rik; sprouty4
Description (Vector)
Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras. Inhibits Ras-independent, but not Ras-dependent, activation of RAF1.
Gene ID
24066
Gene Name (Vector)
sprouty homolog 4 (Drosophila)
Gene Symbol
Spry4
ORF Size (aa)
903
RefSeq ID
NM_011898
RefSeq Synonyms
NM_011898, BC057005, BC050944,
Species
mouse
UniGene ID
Mm.42038

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.