mouse SOCS4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Socs4.
shADV-272834
Ad-m-SOCS4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Socs4 (suppressor of cytokine signaling 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
3110032M18Rik; A730004F22Rik; AI427843; AU015727; AU015859; Socs7
Description (Vector)
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits for instance EGF signaling by mediating the degradation of the EGF receptor/EGFR.
Gene ID
67296
Gene Name (Vector)
suppressor of cytokine signaling 4
Gene Symbol
Socs4
ORF Size (aa)
1311
ORF Size (bp)
1311 bp
RefSeq ID
NM_080843
RefSeq Synonyms
NM_080843, BC117815, BC117814,
Species
mouse
UniGene ID
Mm.425886
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.