mouse SLCO4C1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Slco4c1.
shADV-272551
Ad-m-SLCO4C1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Slco4c1 (solute carrier organic anion transporter family, member 4C1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
9530051F04; C330017E21Rik; OATP-H; OATP-M1; oatp-R; OATP4C1; OATPX; PRO2176; SLC21A20
Description (Vector)
Organic anion transporter, capable of transporting pharmacological substances such as digoxin, ouabain, thyroxine, methotrexate and cAMP. May participate in the regulation of membrane transport of ouabain. Involved in the uptake of the dipeptidyl peptidase-4 inhibitor sitagliptin and hence may play a role in its transport into and out of renal proximal tubule cells. May be involved in the first step of the transport pathway of digoxin and various compounds into the urine in the kidney. May be involved in sperm maturation by enabling directed movement of organic anions and compounds within or between cells. This ion-transporting process is important to maintain the strict epididymal homeostasis necessary for sperm maturation. May have a role in secretory functions since seminal vesicle epithelial cells are assumed to secrete proteins involved in decapacitation by modifying surface proteins to facilitate the acquisition of the ability to fertilize the egg.
Gene ID
227394
Gene Name (Vector)
solute carrier organic anion transporter family, member 4C1
Gene Symbol
Slco4c1
ORF Size (aa)
2169
ORF Size (bp)
2169 bp
RefSeq ID
NM_172658
RefSeq Synonyms
NM_172658, BC119022,
Species
mouse
UniGene ID
Mm.11662
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.