mouse SH2B2 shRNA silencing Adenovirus

Name 
Ad-m-SH2B2-shRNA
Cat No 
shADV-271874
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Sh2b2.

shADV-271874
Ad-m-SH2B2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Sh2b2 (SH2B adaptor protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Aps
Description (Vector)
Adapter protein for several members of the tyrosine kinase receptor family. Involved in multiple signaling pathways. May be involved in coupling from immunoreceptor to Ras signaling. Acts as a negative regulator of cytokine signaling in collaboration with CBL. Binds to EPOR and suppresses EPO-induced STAT5 activation, possibly through a masking effect on STAT5 docking sites in EPOR. Suppresses PDGF-induced mitogenesis. May induce cytoskeletal reorganization via interaction with VAV3.
Gene ID
23921
Gene Name (Vector)
SH2B adaptor protein 2
Gene Symbol
Sh2b2
ORF Size (aa)
1866
ORF Size (bp)
1866 bp
RefSeq ID
NM_018825
RefSeq Synonyms
NM_018825, NM_001302939, NM_001302938, BC057334,
Species
mouse
UniGene ID
Mm.425294

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.