mouse SFRP1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Sfrp1.
shADV-271801
Ad-m-SFRP1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Sfrp1 (secreted frizzled-related protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2210415K03Rik; AW011917; AW107218; AW742929; sFRP-1
Description (Vector)
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.
Gene ID
20377
Gene Name (Vector)
secreted frizzled-related protein 1
Gene Symbol
Sfrp1
ORF Size (aa)
945
RefSeq ID
NM_013834
RefSeq Synonyms
NM_013834, BC094662, BC024495,
Species
mouse
UniGene ID
Mm.281691
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.