mouse SELP shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Selp.
shADV-271577
Ad-m-SELP-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Selp (selectin, platelet). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD antigen CD62P;CD62 antigen-like family member P;CD62P;GMP-140;granule membrane protein 140;Grmp;LECAM3;leukocyte-endothelial cell adhesion molecule 3;PADGEM;platelet activation dependent granule-external membrane protein;P-selectin
Description (eCommerce)
P-Selectin, or CD62P, is a Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. It mediates the interaction of activated endothelial cells or platelets with leukocytes. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P16109].
Description (Vector)
Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1.
Gene ID
20344
Gene Name (eCommerce)
selectin, platelet
Gene Name (Vector)
selectin, platelet
Gene Symbol
Selp
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
2307
ORF Size (bp)
2307 bp
Protein Name (eCommerce)
P-selectin
RefSeq ID
NM_011347
RefSeq Synonyms
NM_011347, BC109159, BC109158,
Research Areas (Faceted)
immunology,cardiovascular
Species
mouse
Target Sentence
P-Selectin, or CD62P, is a Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. It mediates the interaction of activated endothelial cells or platelets with leukocytes. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P16109].
UniGene ID
Mm.3337
UniProt ID (eCommerce)
Q01102
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.