mouse S100A8 shRNA silencing Adenovirus

Name 
Ad-m-S100A8-shRNA
Cat No 
shADV-271300
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse S100a8.

shADV-271300
Ad-m-S100A8-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse S100a8 (S100 calcium binding protein A8 (calgranulin A)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
60B8Ag; AI323541; B8Ag; Caga; CFAg; CP-10; MRP8; p8
Description (Vector)
Calcium-binding protein. Has antimicrobial activity towards bacteria and fungi. Important for resistance to invasion by pathogenic bacteria. Up-regulates transcription of genes that are under the control of NF-kappa-B. Plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS) (By similarity). Promotes tubulin polymerization. Promotes phagocyte migration and infiltration of granulocytes at sites of wounding. Plays a role as pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1. Extracellular calprotectin binds to target cells and promotes apoptosis. Antimicrobial and proapoptotic activity is inhibited by zinc ions.
Gene ID
20201
Gene Name (Vector)
S100 calcium binding protein A8 (calgranulin A)
Gene Symbol
S100a8
ORF Size (aa)
270
RefSeq ID
NM_013650
RefSeq Synonyms
NM_013650, BC078629,
Species
mouse
UniGene ID
Mm.21567

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.