mouse RRAGB shRNA silencing Adenovirus

Name 
Ad-m-RRAGB-shRNA
Cat No 
shADV-271134
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Rragb.

shADV-271134
Ad-m-RRAGB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Rragb (Ras-related GTP binding B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
89
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. Required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. Involved in the RCC1/Ran-GTPase pathway.
Gene ID
245670
Gene Name (Vector)
Ras-related GTP binding B
Gene Symbol
Rragb
ORF Size (aa)
1125
ORF Size (bp)
1125 bp
RefSeq ID
NM_001004154
RefSeq Synonyms
NM_001004154, BC070407, BC069180,
Species
mouse
UniGene ID
Mm.190922

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.