mouse PSMC3IP shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Psmc3ip.
shADV-269648
Ad-m-PSMC3IP-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Psmc3ip (proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C79099; GT198; HOP2; Tbpip
Description (Vector)
Plays an important role in meiotic recombination. Stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. May inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3. Acts as a tissue specific coactivator of hormone-dependent transcription mediated by nuclear receptors.
Gene ID
19183
Gene Name (Vector)
proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein
Gene Symbol
Psmc3ip
ORF Size (aa)
654
RefSeq ID
NM_008949
RefSeq Synonyms
NM_008949, BC030169,
Species
mouse
UniGene ID
Mm.18344
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.