mouse PRDM5 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Prdm5.
shADV-269311
Ad-m-PRDM5-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Prdm5 (PR domain containing 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4432417F03Rik; 6530401I24Rik; AI197291; E130112L17Rik; PFM2
Description (Vector)
Sequence-specific DNA-binding transcription factor. Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1. Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes. May regulate the expression of proteins involved in extracellular matrix development and maintenance, including fibrillar collagens, such as COL4A1 and COL11A1, connective tissue components, such as HAPLN1, and molecules regulating cell migration and adhesion, including EDIL3 and TGFB2. May caused G2/M arrest and apoptosis in cancer cells.
Gene ID
70779
Gene Name (Vector)
PR domain containing 5
Gene Symbol
Prdm5
ORF Size (aa)
1800
ORF Size (bp)
1800 bp
RefSeq ID
NM_027547
RefSeq Synonyms
NM_029549, NM_027547, BC138902, BC138901,
Species
mouse
UniGene ID
Mm.263355
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.