mouse POLR3H shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Polr3h.
shADV-269058
Ad-m-POLR3H-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Polr3h (polymerase (RNA) III (DNA directed) polypeptide H). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5031409G22Rik; RPC8
Description (Vector)
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
Gene ID
78929
Gene Name (Vector)
polymerase (RNA) III (DNA directed) polypeptide H
Gene Symbol
Polr3h
ORF Size (aa)
615
ORF Size (bp)
615 bp
RefSeq ID
NM_030229
RefSeq Synonyms
NM_030229, BC010793,
Species
mouse
UniGene ID
Mm.215115
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.