mouse POLR2B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Polr2b.
shADV-269033
Ad-m-POLR2B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Polr2b (polymerase (RNA) II (DNA directed) polypeptide B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Pol2rb; Rpb140; Rpb2
Description (Vector)
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template (By similarity).
Gene ID
231329
Gene Name (Vector)
polymerase (RNA) II (DNA directed) polypeptide B
Gene Symbol
Polr2b
ORF Size (aa)
3504
ORF Size (bp)
3504 bp
RefSeq ID
NM_153798
RefSeq Synonyms
NM_153798, BC038472,
Species
mouse
UniGene ID
Mm.273217
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.