mouse PLA2G6 shRNA silencing Adenovirus

Name 
Ad-m-PLA2G6-shRNA
Cat No 
shADV-268781
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Pla2g6.

shADV-268781
Ad-m-PLA2G6-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Pla2g6 (phospholipase A2, group VI). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BB112799; iPLA(2)beta; iPLA2; iPLA2beta; PNPLA9
Description (Vector)
Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation|Function: Isoform ankyrin-iPLA2-1 and isoform ankyrin-iPLA2-2, which lack the catalytic domain, are probably involved in the negative regulation of iPLA2 activity.
Gene ID
53357
Gene Name (Vector)
phospholipase A2, group VI
Gene Symbol
Pla2g6
ORF Size (aa)
2424
ORF Size (bp)
2424 bp
RefSeq ID
NM_016915
RefSeq Synonyms
NM_016915, NM_001199025, NM_001199024, NM_001199023, BC057209, BC052845, BC003487,
Species
mouse
UniGene ID
Mm.155620

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.