mouse PIKFYVE shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Pikfyve.
shADV-268659
Ad-m-PIKFYVE-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Pikfyve (phosphoinositide kinase, FYVE finger containing). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5230400C17Rik; p235; Pip5k; Pip5k3; Pipk5k3; PipkIII
Description (Vector)
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the phosphorylation of phosphatidylinositol 3-phosphate on the fifth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 3,5-bisphosphate. Required for endocytic-vacuolar pathway and nuclear migration. Plays a role in the biogenesis of endosome carrier vesicles (ECV)/ multivesicular bodies (MVB) transport intermediates from early endosomes.
Gene ID
18711
Gene Name (Vector)
phosphoinositide kinase, FYVE finger containing
Gene Symbol
Pikfyve
ORF Size (aa)
6156
ORF Size (bp)
6156 bp
RefSeq ID
NM_011086
RefSeq Synonyms
NM_011086, NM_001310624, BC148367,
Species
mouse
UniGene ID
Mm.38370
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.