mouse PEO1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Twnk.
shADV-268396
Ad-m-PEO1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Twnk (twinkle mtDNA helicase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
D19Ertd626e; PEO; Peo1; Twinl
Description (Vector)
Involved in mitochondrial DNA (mtDNA) metabolism. Could function as an adenine nucleotide-dependent DNA helicase. Function inferred to be critical for lifetime maintenance of mtDNA integrity. In vitro, forms in combination with POLG, a processive replication machinery, which can use double-stranded DNA (dsDNA) as template to synthesize single-stranded DNA (ssDNA) molecules. May be a key regulator of mtDNA copy number in mammals (By similarity).
Gene ID
226153
Gene Name (Vector)
twinkle mtDNA helicase
Gene Symbol
Twnk
ORF Size (aa)
2058
ORF Size (bp)
2058 bp
RefSeq ID
NM_153796
RefSeq Synonyms
NM_153796, BC071195,
Species
mouse
UniGene ID
Mm.105585
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.