mouse PARD3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Pard3.
shADV-268064
Ad-m-PARD3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Pard3 (par-3 family cell polarity regulator). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AA960621; AI256638; Asip; D8Ertd580e; Par-3; Par3; Pard-3; Pard3a; Phip
Description (Vector)
Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.
Gene ID
93742
Gene Name (Vector)
par-3 family cell polarity regulator
Gene Symbol
Pard3
ORF Size (aa)
3915
ORF Size (bp)
3915 bp
RefSeq ID
NM_001013580
RefSeq Synonyms
NM_033620, NM_001309392, NM_001309391, NM_001122850, NM_001013581, NM_001013580, BC145508, BC141187, BC090616,
Species
mouse
UniGene ID
Mm.299254
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.