mouse NPHP3 shRNA silencing Adenovirus

Product Info

Knockdown

>60% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Nphp3

Gene Name

nephronophthisis 3 (adolescent)

Gene ID

74025

Gene Synonyms

3632410F03Rik; AI550417; C230078J01; D330020E01Rik; pcy

ORF Size

3615 bp

RefSeq#

NM_028721

Gene Description

Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.

UniGene ID

Mm.41274