mouse NLRP2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Nlrp2.
shADV-265848
Ad-m-NLRP2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Nlrp2 (NLR family, pyrin domain containing 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
E330007A02Rik; Nalp2; NBS1; PAN1; PYPAF2
Description (Vector)
Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
Gene ID
232827
Gene Name (Vector)
NLR family, pyrin domain containing 2
Gene Symbol
Nlrp2
ORF Size (aa)
3141
ORF Size (bp)
3141 bp
RefSeq ID
NM_177690
RefSeq Synonyms
NM_177690, BC156633,
Species
mouse
UniGene ID
Mm.246598
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.