mouse NKIRAS2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Nkiras2.
shADV-265804
Ad-m-NKIRAS2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Nkiras2 (NFKB inhibitor interacting Ras-like protein 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2410003M04Rik; 4930527H08Rik; D630018G21Rik; KBRAS2
Description (Vector)
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity).
Gene ID
71966
Gene Name (Vector)
NFKB inhibitor interacting Ras-like protein 2
Gene Symbol
Nkiras2
ORF Size (aa)
576
ORF Size (bp)
576 bp
RefSeq ID
NM_028024
RefSeq Synonyms
NM_028024, BC024398, BC013469,
Species
mouse
UniGene ID
Mm.274734
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.