mouse NFE2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Nfe2.
shADV-265708
Ad-m-NFE2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Nfe2 (nuclear factor, erythroid derived 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NF-E2; NF-E2/P45; p45; p45nf-e2; p45NFE2
Description (Vector)
Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Gene ID
18022
Gene Name (Vector)
nuclear factor, erythroid derived 2
Gene Symbol
Nfe2
ORF Size (aa)
1122
ORF Size (bp)
1122 bp
RefSeq ID
NM_008685
RefSeq Synonyms
NM_008685, NM_001302343, NM_001302341, NM_001302340, NM_001302339, NM_001302338, BC062171,
Species
mouse
UniGene ID
Mm.457989
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.