mouse NEIL2 shRNA silencing Adenovirus

Name
Ad-m-NEIL2-shRNA

Cat No
shADV-265639

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Neil2.

shADV-265639

Ad-m-NEIL2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Neil2 (nei like 2 (E. coli)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

Gm1212; NEH2

Description (Vector)

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5-hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double stranded DNA (DNA bubbles). Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.

Gene ID

382913

Gene Name (Vector)

nei like 2 (E. coli)

Gene Symbol

Neil2

ORF Size (aa)

834

ORF Size (bp)

834 bp

RefSeq ID

NM_201610

RefSeq Synonyms

NM_201610, BC115762,

Species

mouse

UniGene ID

Mm.239490

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.