mouse NDRG1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Ndrg1.
shADV-265546
Ad-m-NDRG1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ndrg1 (N-myc downstream regulated gene 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CAP43; CMT4D; DRG1; HMSNL; Ndr1; Ndrl; NMSL; PROXY1; RTP; TDD5
Description (Vector)
Stress-responsive protein involved in hormone responses, cell growth, and differentiation. Acts as a tumor suppressor in many cell types. Necessary but not sufficient for p53/TP53-mediated caspase activation and apoptosis. Has a role in cell trafficking, notably of the Schwann cell, and is necessary for the maintenance and development of the peripheral nerve myelin sheath. Required for vesicular recycling of CDH1 and TF. May also function in lipid trafficking. Protects cells from spindle disruption damage. Functions in p53/TP53-dependent mitotic spindle checkpoint. Regulates microtubule dynamics and maintains euploidy.
Gene ID
17988
Gene Name (Vector)
N-myc downstream regulated gene 1
Gene Symbol
Ndrg1
ORF Size (aa)
1185
ORF Size (bp)
1185 bp
RefSeq ID
NM_008681
RefSeq Synonyms
NM_008681, BC171968, BC141246, BC071235, BC015282,
Species
mouse
UniGene ID
Mm.30837
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.