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mouse MYO10 shRNA silencing Adenovirus

Name 
Ad-m-MYO10-shRNA
Cat No 
shADV-265318
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Myo10.

shADV-265318
Ad-m-MYO10-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Myo10 (myosin X). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AW048724; D15Ertd600e; mKIAA0799; myosin-X
Description (Vector)
Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. MYO10 binds to actin filaments and actin bundles and functions as plus end-directed motor. The tail domain binds to membranous compartments containing phosphatidylinositol 3,4,5-trisphosphate or integrins, and mediates cargo transport along actin filaments. Regulates cell shape, cell spreading and cell adhesion. Stimulates the formation and elongation of filopodia. May play a role in neurite outgrowth and axon guidance. Plays a role in formation of the podosome belt in osteoclasts (By similarity).
Gene ID
17909
Gene Name (Vector)
myosin X
Gene Symbol
Myo10
ORF Size (aa)
6189
ORF Size (bp)
6189 bp
RefSeq ID
NM_019472
RefSeq Synonyms
NM_019472, BC157051, BC156151,
Species
mouse
UniGene ID
Mm.60590

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.