mouse MUL1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Mul1.
shADV-265196
Ad-m-MUL1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mul1 (mitochondrial ubiquitin ligase activator of NFKB 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
0610009K11Rik; AV000801; Gide
Description (Vector)
Exhibits weak E3 ubiquitin-protein ligase activity, but preferentially acts as a SUMO E3 ligase at physiological concentrations. Plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Gene ID
68350
Gene Name (Vector)
mitochondrial ubiquitin ligase activator of NFKB 1
Gene Symbol
Mul1
ORF Size (aa)
1059
ORF Size (bp)
1059 bp
RefSeq ID
NM_026689
RefSeq Synonyms
NM_026689, BC019516,
Species
mouse
UniGene ID
Mm.103413
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.