mouse MNAT1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Mnat1.
shADV-264751
Ad-m-MNAT1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mnat1 (menage a trois 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
E130115E11Rik; MAT1; P36
Description (Vector)
Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
Gene ID
17420
Gene Name (Vector)
menage a trois 1
Gene Symbol
Mnat1
ORF Size (aa)
930
RefSeq ID
NM_008612
RefSeq Synonyms
NM_008612, BC115630, BC089023,
Species
mouse
UniGene ID
Mm.246750
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.