mouse MIF shRNA silencing Adenovirus

Name
Ad-m-MIF-shRNA

Cat No
shADV-264643

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Mif.

shADV-264643

Ad-m-MIF-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mif (macrophage migration inhibitory factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

GIF; Glif

Description (Vector)

Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.

Gene ID

17319

Gene Name (Vector)

macrophage migration inhibitory factor

Gene Symbol

Mif

ORF Size (aa)

348

RefSeq ID

NM_010798

RefSeq Synonyms

NM_010798, BC100605, BC086928, BC024895,

Species

mouse

UniGene ID

Mm.2326

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.