mouse MGRN1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Mgrn1.
shADV-264613
Ad-m-MGRN1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mgrn1 (mahogunin, ring finger 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2610042J20Rik; md; mKIAA0544; nc
Description (Vector)
E3 ubiquitin-protein ligase. Mediates monoubiquitination at multiple sites of TSG101 in the presence of UBE2D1, but not of UBE2G1, nor UBE2H. Plays a role in the regulation of endosome-to-lysosome trafficking. Impairs MC1R- and MC4R-signaling by competing with GNAS-binding to MCRs and inhibiting agonist-induced cAMP production. Does not inhibit ADRB2-signaling. Does not promote MC1R ubiquitination.
Gene ID
17237
Gene Name (Vector)
mahogunin, ring finger 1
Gene Symbol
Mgrn1
ORF Size (aa)
1599
ORF Size (bp)
1599 bp
RefSeq ID
NM_029657
RefSeq Synonyms
NM_029657, NM_001252437, BC046830,
Species
mouse
UniGene ID
Mm.391848
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.