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mouse MGAT5B shRNA silencing Adenovirus

Name 
Ad-m-MGAT5B-shRNA
Cat No 
shADV-264596
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Mgat5b.

shADV-264596
Ad-m-MGAT5B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mgat5b (mannoside acetylglucosaminyltransferase 5, isoenzyme B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C330018B01; GnT-IX; mGnTVB
Description (Vector)
Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAcbeta1,2-Manalpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAcbeta1,2-Manalpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway.
Gene ID
268510
Gene Name (Vector)
mannoside acetylglucosaminyltransferase 5, isoenzyme B
Gene Symbol
Mgat5b
ORF Size (aa)
2379
ORF Size (bp)
2379 bp
RefSeq ID
NM_172948
RefSeq Synonyms
NM_172948, BC094604,
Species
mouse
UniGene ID
Mm.35141

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.